-  Extract patch (p28574555_122010_MSWIN-x86-64.zip) to a folder (C:\) 
-  set ORACLE_HOME=C:\Oracle\product\12.2.0\dbhome_1 
-  set PATH=%ORACLE_HOME%\bin;%ORACLE_HOME%\OPatch 
-  cd C:\p28574555_122010_MSWIN-x86-64\28574555 
-  stop all Oracle instances 
-  opatch apply 
-  if everything went ok: “OPatch succeeded.”